Peptides are among the vital content of several cosmetic and health products. It has many uses, including anti-inflammatory, anti-aging, and muscle-building properties. There are many types of Peptides for sale in the market for your specific needs. Meanwhile, in this article, we will discuss Peptide Reconstruction.
The structural characterizations of protein-peptide complexes may need improvements. It includes reconstruction of the mussing structure optimization for higher accuracy models of the peptide.
How are peptides reconstructed?
Protein-peptides models can be reconstructed from their C-alpha traces to all-atom representation with the use of MODELLED. Then, they will be refined with Rosetta FlexPepDock. Then the described workflow can help for the efficient all-atom reconstruction of CABS-dock models and improve high-resolution models.
Peptides also have the potential for cancer therapy. According to clinical research, it may slow down the symptoms of the disease. Researchers focus on the modification and reconstruction of ACP or anti-cancer peptides. It helps to make the best of its advantages.
The peptide reconstruction is divided into side chain modification and main chain reconstruction.
Main chain reconstruction
It is the replacement of non-natural or natural amino acids. The sequence and type of amino acids are crucial to the function and structure of short peptides. The most effective method of modifying ACP is to change the main chain amino acid type.
In this peptide reconstruction, amino acids’ substitution can result in changes in hydrophobicity, net charge, and velocity that can also change the selectivity and activity.
Side chain modification
The side chain modification involves polyethylene glycol (PEG) modification, cholesterol modification phosphorylation, palmitoylation, and glycosylation.
It includes phosphorylation which is a pervasive peptide or protein modification after being synthesized. The side chain modification also includes polyethylene glycol modification which is the coupling of PEG groups with free side chain groups on the peptides’ molecular surface on the covalent bonds. It aimed to change the peptides’ chemical properties.
Importance of Peptide Reconstruction
Peptide reconstruction is beneficial for the improvement of peptide use. The reconstruction of peptides is also essential to reduce their side effects and maintain their advantages. More importantly, it can also improve peptides’ therapeutic properties.
With peptide reconstruction, you can get the essential benefits of peptides. If you don’t have an idea about the benefits of peptides, read more.
Advantages of Peptides
Peptides come with many potential benefits to your health. These include:
Slows down the aging process
Skin, nails, and hair contain protein which is called collagen. Well, collagen peptides can be easily absorbed by the body. As you take collagen peptides, you can slow down the aging process and enhance your skin health.
Avoids age-related bone loss
It also helps to prevent bone loss related to aging.
Build muscle mass and strength
By consuming collagen peptide supplements, you can improve your muscle strength and mass. Don’t worry because these peptides are easy to digest.
Improve healing of wounds
Collagen peptides can heal your wound faster. It also lowers inflammation and serves as an antioxidant that can improve your body’s healing process.
You can Buy Peptides online according to your specific needs. However, make sure to take it according to its instructions.